An underground economy for unapproved weight-loss drugs is being driven by TikTok fitness influencers and sellers on communication apps, according to recent findings.
The experimental drug, which remains in clinical trials, is being advertised by social media influencers for its supposed fat-burning effects. Followers are urged to contact these profiles directly for supplier links, while also receiving promotional offers.
Separately, a flourishing trade exists on messaging services, where groups with thousands of members share “before and after” images, injection guides and assertions of next-day British shipping. Vendors promote the drug there before directing customers to other platforms for purchases.
Retatrutide is an experimental injectable developed by US drugmaker Eli Lilly. The treatment affects three intestinal hormones – GLP-1, GIP and pancreatic hormone. Preliminary studies indicate it could help individuals reduce up to 25% of their body weight. Nicknamed the “triple G”, the substance is being hailed online as the next Ozempic.
However, doctors and chemists have cautions that the sale of what is still an unapproved drug in the United Kingdom is a cause for concern and could result in users injecting substances of unknown origin.
Some experts said the demand for the experimental drug could be linked to the increasing cost of licensed weight loss products such as Mounjaro.
Selling retatrutide on TikTok or Telegram is prohibited in the United Kingdom, as it is an unlicensed medication that must not be promoted or distributed for personal consumption under the Human Medicines Regulations 2012.
Several influencers attempt to circumvent the regulations by calling to the drug as a “research chemical” or describing it as “not for human consumption”. Retatrutide is not a controlled drug, but advertising and distribution can still breach pharmaceutical, marketing, and consumer regulations, risking fines, prosecution or prison.
Based on TikTok, the platform has taken down violative content and prohibited associated hashtags and query recommendations. The organization stated it was committed to keeping the platform secure and allocating resources in enhancing compliance measures.
Investigations also discovered groups with up to 9,000 members marketing retatrutide using the platform's integrated search feature, which operates like a public directory. Entering “retatrutide” immediately brings up groups with numerous of users, populated with photos of weight loss, glowing reviews and detailed guides for mixing or administering at residence.
Within minutes of joining one group, a seller shared WhatsApp details, where the majority of purchases occur. The vendor provided an instruction manual and promised shipping within 48 hours. When asked whether the substance was genuine, one seller said: “You can’t be sure.” Another shared a photo of a alleged testing documentation. Not one inquired about weight, medical conditions or past usage.
Within these groups, messages show dark colored packages with postal service stickers, stating to include fresh supplies. One message stated: “It took eight of us to load them this morning.”
Buyers can choose between powder vials, prepared at residence with purified liquid, or pre-filled pens usually priced at £160 for 20 milligrams. When asked how much time a pen should be used, vendors give conflicting answers ranging from a several days to “depends on your body”.
A representative for the messaging service said it regularly monitored dangerous content on its platform including content that promoted the “misuse of controlled medications”. The organization added that it removed “millions of pieces of harmful content each day”.
“People are injecting substances they can’t verify. Even if the research behind retatrutide is valid, these digital products may not include what they claim,” stated a pharmacy expert, the director of pharmaceutical services at Chemist4U.
Dr Crystal Wyllie of Asda Online Doctor linked the surge in demand to recent price rises for approved weight-loss drugs such as Mounjaro. “With prices increasing, patients are turning to online platforms. But fake injections are extremely dangerous. You can’t be certain what’s contained or whether the environment they were made in was clean,” she explained.
Her team has already seen patients harmed by self-injection from unverified sources. “We recognize the frustration, but purchasing from messaging apps or WhatsApp is taking chances with your health,” said the doctor. “These substances could be contaminated or incorrectly dosed.”
A spokesperson from Eli Lilly stated the substance was in third stage research studies and had not been evaluated or approved by any government authority anywhere in the world. “Therefore at this point no one can sell [it] for human use,” they explained, noting that any product “falsely representing itself as a Lilly investigational product not yet authorized … may expose users to potentially significant health risks”.
Education enthusiast and certified tutor with a passion for helping students achieve their academic goals through innovative learning methods.